In Washington D.C., an American senator is the victim of a depraved murder. In London, a senior member of parliament is brutally slain in the tunnels beneath Whitehall. Only one thing appears to link the American and British politicians – the archaic ritual used to kill them.

As wayward intelligence operative Blake Carver hunts for the perpetrators, he discovers an ancient order of assassins thought to have been dissolved centuries ago. During an epic chase that takes him from the corridors of Washington to the wilds of South Africa and the catacombs of Rome, he finds himself caught in a shadow war that threatens to engulf the entire world.